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The human genome has been referred to as the blueprint of human biology. An essential, but largely ignored overlay to that blueprint is the human microbiome.
The human microbiome is a source of Genetic Diversity, a modifier of disease, an essential component of immunity, and a functional “entity” that influencing metabolism and modulating systemic biochemistry.
It is the aggregate of all microbiota that reside on or within human tissues and biofluids, including the corresponding anatomical sites in which they reside. The commensal microbiota that inhabit different parts of the GI tract has been shaped by co-evolution with the host species. The symbiotic relationship of the hundreds of microbial species with the host requires a tuned response that prevents host damage while innately integrating the presence of beneficial microbes. French physiologist Claude Bernard’s concept of milieu intérieur (internal environment) attempting to establish the determinants of a healthy immune response by identifying genetic and environmental factors that contribute to the multi-heterogeneity of the “terrain”.
The development of probiotic formulas has moved beyond the inclusion of general, generic groups of organisms, to defining specific strains. Many probiotic formulations list their probiotics without identification of the specific strain or the amounts. Symbiome CMF-50B includes only probiotics that have been identified by genomic sequencing and registered with a specific strain identification. This is important as these strain-specific probiotics have undergone rigorous genomic studies guaranteeing accurate specificity and potency. These are the robust strains capable of surviving the inhospitable transport to the intestines where they attach to the intestinal walls to grow and function to effectively sustain GI health and systemic terrain.
Our veggie acid-resistant pH targeted release capsules pass unaltered through digestive acidic and bile resistant conditions to disintegrate in the higher pH levels of the duodenum where they are transported to GALT (gut-associated lymphatic tissue) lymphatic tissues & Peyer’s patches’ immune cells. This design insures that the formula is delivered intact to fortify the systemic microbiome and support immune & hormonal function, lungs, brain challenges, skin, digestive and vaginal imbalances, etc.
The bidirectional communication between the brain and the gastrointestinal tract, the so-called “brain-gut-brain axis,” is based on a complex system, including the vagus nerve, but also the sympathetic via the prevertebral ganglia, endocrine, immune, and humoral links. This requires a healthy gut microbiota to regulate gastrointestinal homeostasis and to connect emotional and cognitive areas of the brain with gut functions.
These 10 highly researched probiotic strains and the nutrient-rich host medium of Symbiome CMF-50B have been meticulously designed to nutritionally support the specific pathways and components vital to the creation of a wholesome microbiome pattern establishing the foundation for a powerful, targeted, and poly-systemic Causal Chain healing milieu.